Table 3.
Regulated genes by combination of H. pylori infection and high-salt diet in mouse gastric mucosa
| Accession no. | Symbol | Genes/proteins | Fold changes |
|---|---|---|---|
|
Up-regulated genes | |||
|
XM_357640 |
Igk-V8 |
Immunoglobulin kappa chain variable 8 (V8) |
14.4 |
|
XM_001472541 |
Ighg |
Immunoglobulin heavy chain (gamma polypeptide) |
9.2 |
|
NM_026862 |
Cd177 |
CD177 antigen |
7.3 |
|
NM_011260 |
Reg3g |
Regenerating islet-derived 3 gamma |
6.1 |
|
NM_023137 |
Ubd |
Ubiquitin D |
4.3 |
|
XM_144817 |
Igk-V34 |
Immunoglobulin kappa chain variable 34 (V34) |
4.1 |
|
NM_007675 |
Ceacam10 |
Carcinoembryonic antigen-related cell adhesion molecule 10 |
3.7 |
|
NM_183322 |
Khdc1a |
KH domain containing 1A |
3.3 |
|
NM_011475 |
Sprr2i |
Small proline-rich protein 2I |
3.2 |
|
NM_175165 |
Tprg |
Transformation related protein 63 regulated |
3.2 |
|
NM_175406 |
Atp6v0d2 |
ATPase, H+ transporting, lysosomal V0 subunit D2 |
3.0 |
|
NM_009703 |
Araf |
v-raf murine sarcoma 3611 viral oncogene homolog |
2.6 |
|
NM_026822 |
Lce1b |
Late cornified envelope 1B |
2.5 |
|
NM_016958 |
Krt14 |
Keratin 14 |
2.5 |
|
NM_212487 |
Krt78 |
Keratin 78 |
2.4 |
|
NM_009807 |
Casp1 |
Caspase 1 |
2.4 |
|
NM_146037 |
Kcnk13 |
Potassium channel, subfamily K, member 13 |
2.4 |
|
NM_019450 |
Il1f6 |
Interleukin 1 family, member 6 |
2.3 |
|
NM_008827 |
Pgf |
Placental growth factor |
2.3 |
|
XM_893506 |
Klk12 |
Kallikrein related-peptidase 12 |
2.3 |
|
NM_016887 |
Cldn7 |
Claudin 7 |
2.3 |
|
NM_029360 |
Tm4sf5 |
Transmembrane 4 superfamily member 5 |
2.2 |
|
NM_172301 |
Ccnb1 |
Cyclin B1 |
2.2 |
|
NM_010739 |
Muc13 |
Mucin 13, epithelial transmembrane |
2.2 |
|
NM_011165 |
Prl4a1 |
Prolactin family 4, subfamily a, member 1 |
2.2 |
|
NM_010162 |
Ext1 |
Exostoses (multiple) 1 |
2.2 |
|
NM_011704 |
Vnn1 |
Vanin 1 |
2.1 |
|
NM_011082 |
Pigr |
Polymeric immunoglobulin receptor |
2.1 |
|
NM_007769 |
Dmbt1 |
Deleted in malignant brain tumors 1 |
2.1 |
|
NM_022984 |
Retn |
Resistin |
2.1 |
|
NM_173037 |
Tmco 7 |
Transmembrane and coiled-coil domain 7 |
2.1 |
|
NM_009100 |
Rptn |
Repetin |
2.1 |
|
NM_007630 |
Ccnb2 |
Cyclin B2 |
2.1 |
|
NM_001081060 |
Slc9a3 |
Solute carrier family 9 (sodium/hydrogen exchanger), member 3 |
2.0 |
|
NM_146588 |
Olfr1030 |
Olfactory receptor 1030 |
2.0 |
|
Down-regulated genes | |||
|
NM_008753 |
Oaz1 |
Ornithine decarboxylase antizyme 1 |
0.31 |
|
NM_027126 |
Hfe2 |
Hemochromatosis type 2 (juvenile) (human homolog) |
0.33 |
|
NM_053206 |
Magee2 |
Melanoma antigen, family E, 2 |
0.33 |
|
NM_010924 |
Nnmt |
Nicotinamide N-methyltransferase |
0.41 |
|
NM_026260 |
Tctn3 |
Tectonic family member 3 |
0.41 |
|
NM_181039 |
Lphn1 |
Latrophilin 1 |
0.43 |
|
NM_008312 |
Htr2c |
5-hydroxytryptamine (serotonin) receptor 2C |
0.43 |
|
NM_146667 |
Olfr740 |
Olfactory receptor 740 |
0.44 |
|
NM_007550 |
Blm |
Bloom syndrome homolog (human) |
0.44 |
|
NM_011243 |
Rarb |
Retinoic acid receptor, beta |
0.44 |
|
NM_184052 |
Igf1 |
Insulin-like growth factor 1 |
0.45 |
|
NM_013893 |
Reg3d |
Regenerating islet-derived 3 delta |
0.46 |
|
NM_008645 |
Mug1 |
Murinoglobulin 1 |
0.46 |
|
NM_029550 |
Keg1 |
Kidney expressed gene 1 |
0.46 |
|
NM_019388 |
Cd86 |
CD86 antigen |
0.46 |
|
NM_011316 |
Saa4 |
Serum amyloid A 4 |
0.47 |
|
NM_007811 |
Cyp26a1 |
Cytochrome P450, family 26, subfamily a, polypeptide 1 |
0.47 |
|
NM_011538 |
Tbx6 |
T-box 6 |
0.48 |
|
NM_011086 |
Pip5k3 |
Phosphatidylinositol-3-phospate/phosphatidylinositol 5-kinase, type III |
0.48 |
|
NM_133723 |
Asph |
Aspartate-beta-hydroxylase |
0.48 |
|
NM_001081390 |
Palld |
Palladin, cytoskeletal associated protein |
0.48 |
|
NM_007858 |
Diap1 |
Diaphanous homolog 1 (Drosophila) |
0.48 |
|
NM_053271 |
Rims2 |
Regulating synaptic membrane exocytosis 2 |
0.48 |
|
NM_153163 |
Cadps2 |
Ca2+-dependent activator protein for secretion 2 |
0.49 |
|
NM_007541 |
Bglap1 |
Bone gamma carboxyglutamate protein 1 |
0.49 |
|
NM_031871 |
Ghdc |
GH3 domain containing |
0.49 |
|
NM_025545 |
Aptx |
Aprataxin |
0.49 |
|
NM_177322 |
Agtr1a |
Angiotensin II receptor, type 1a |
0.49 |
|
NM_026872 |
Ubap2 |
Ubiquitin-associated protein 2 |
0.49 |
|
NM_028045 |
Erv3 |
Endogenous retroviral sequence 3 |
0.49 |
| NM_011641 | Trp63 | Transformation related protein 63 | 0.49 |