Table 1.
Main demographic, clinical and MRI characteristics of HLA-A2+ patients
| Patient | Gender | Age | Duration (years) | Predominant symptoms | MRI Gd enhancement | EDSS |
|---|---|---|---|---|---|---|
| 1 |
F |
48 |
1 |
motor |
- |
6 |
| 2 |
F |
20 |
2 |
brainstem, ON |
+ |
2 |
| 3 |
F |
51 |
4 |
brainstem |
+ |
3 |
| 4 |
F |
29 |
3 |
cerebellar, sensitive |
+ |
3 |
| 5 |
F |
37 |
1 |
brainstem |
- |
1 |
| 6 |
F |
53 |
7 |
brainstem |
- |
0 |
| 7 |
F |
40 |
1 |
sensitive |
- |
2 |
| 8 |
M |
39 |
1 |
cerebellar |
- |
1 |
| 9 |
F |
40 |
2 |
ON |
- |
1 |
| 10 |
F |
38 |
1 |
ON, sensitive |
- |
2 |
| 11 |
M |
49 |
1 |
ON |
- |
1 |
| 12 |
F |
46 |
1 |
sensitive |
- |
1 |
| 13 |
M |
24 |
1 |
sensitive, ON |
- |
1 |
| 14 |
M |
49 |
20 |
motor, ataxia |
- |
4 |
| 15 |
F |
43 |
1 |
sensitive |
- |
2 |
| 16 |
F |
34 |
2 |
sphincteric, ON |
+ |
3 |
| 17 |
F |
61 |
5 |
brainstem, vertigo |
- |
1 |
| 18 |
F |
40 |
3 |
sensitive |
- |
3 |
| 19 |
M |
43 |
2 |
motor |
- |
5 |
| 20 |
F |
35 |
1 |
motor |
- |
1 |
| 21 |
F |
43 |
5 |
motor |
- |
4 |
| 22 |
M |
32 |
6 |
motor |
+ |
7 |
| 23 |
F |
53 |
4 |
motor, ataxia |
+ |
4 |
| 24 |
F |
19 |
1 |
brainstem |
+ |
1 |
| 25 |
F |
43 |
9 |
sensitive, brainstem |
+ |
2 |
| 26 | F | 53 | 4 | sensitive, motor | + | 3 |
All patients had relapsing remitting MS, except for patients 1 and 14 who had secondary-progressive MS.
Legend: ON, optic neuritis; EDSS, expanded disability status scale; MRI Gd enhancement, nuclear magnetic resonance gadolinium enhancement.