Table 3. Selected overrepresented functional categories for differentially expressed genes in High Fertile as compared to Infertile heifers (nominal P-value <0.01).
| Representative enriched functional terms1 | Enrich-ment Score2 | No. Genes |
| Selected terms for genes with lower expression in HF as compared to IF group | ||
| Macromolecular complex subunit organization (12, 2.8); chromatin (7, 5.7); ubl conjugation (9, 2.5); heterogeneous nuclear ribonucleoprotein M (6,2.6) | 1.94 | 26 |
| RNA binding (10, 2.1) | 1.58 | 10 |
| Topological domain:Lumenal (8, 3.0); signal-anchor (6, 2.4) | 1.36 | 8 |
| Zinc finger, RING-type (6, 3.2); Zinc finger, C3HC4 RING-type (5, 3.4) | 1.24 | 6 |
| Mitochondrion (11, 1.6); organelle envelope (9, 2.3); mitochondrial inner membrane (5, 2.6) | 1.21 | 14 |
| Manganese ion binding (4, 3.9) | 1.15 | 4 |
| Selected terms for genes with higher expression in HF as compared to IF group | ||
| ATPase activity (5, 2.7); ATPase, AAA+ type, core (4, 5.1) | 1.29 | 5 |
| Protein kinase cascade (6, 2.9); MAPKKK cascade (6, 5.8); regulation of cellular protein metabolic process (6, 2.3) | 1.22 | 10 |
| Oxidation reduction (8, 2.2); oxidoreductase (7, 2.4) | 1.18 | 8 |
| Cell projection (8, 2.0); neuron projection (5, 2.6) | 1.05 | 8 |
| Lytic vacuole (4, 3.4); lysosome (4, 3.4) | 1.02 | 4 |
1
in brackets: number of genes and fold enrichment of the functional term; 2geometric mean (in -log10 scale) of member's p-values of the corresponding annotation cluster.