Figure 4.

Effect of Dioscorea villosa (DV) on leukocyte migration into the peritoneal cavity induced by carrageenan in mice. Groups of rats were pre-treated with vehicle (control group, 10 mL/Kg, per os or p.o.), dexamethasone (Dexa, 2 mg/kg, s.c.), or DV in concentrations of 100, 200 and 400 mg/kg (per os or p.o.) 60 min before carrageenan (500 μg/cavity, 500 μL, i.p.)-induced peritonitis. Cell counts were performed at the time 4 h after the injection of carrageenan. Value represents the mean ± S.E.M. *p < 0.05 and **P < 0.001 when compared to control group. ANOVA followed by Tukey test (n = 6, per group).