Table 8.
Serum biochemical findings in rats Wistar treated with Dioscorea villosa at a single dose (5 g/kg)
| Parameters | FC | FT | R1 Female | MC | MT | R1 Male |
|---|---|---|---|---|---|---|
| Albumin (g/dL) |
3.06 ± 0.097 |
3.06 ± 0.030 |
2.6 – 3.4 a |
3.03 ± 0.112 |
2.73 ± 0.042* |
2.7 – 3.2 a |
| ALP (U/L) |
48.00 ± 4.669 |
73.43 ± 5.622** |
63 – 138 a |
80.00 ± 4.889 |
109.4 ± 6.575** |
79 – 196 a |
| TGP or ALT (U/L) |
40.60 ± 3.614 |
51.57 ± 2.999* |
26 – 60 a |
68.43 ± 7.234 |
62.43 ± 2.653 |
36 – 58 a |
| TGO or AST (U/L) |
106.80 ± 8.509 |
86.00 ± 5.499 |
83 – 184 a |
160.9 ± 15.33 |
121.1 ± 14.12 |
81 – 180 a |
| Creatinine (mg/dL) |
0.49 ± 0.007 |
0.5329 ± 0.015 |
0.4 – 0.7 a |
0.59 ± 0.019 |
0.51 ± 0.007** |
0.44 – 0.64 a |
| GLUC (mg/dL) |
131.40 ± 7.593 |
161.7 ± 5.222** |
61 - 147 a |
157.6 ± 7.030 |
172.7 ± 7.819 |
79 – 144 a |
| K+ (mmol/L) |
4.05 ± 0.193 |
4.06 ± 0.146 |
3.7 – 5.7 a |
5.814 ± 0.370 |
5.07 ± 0.185 |
4.2 – 6.4 a |
| Na+ (mmol/L) |
133.40 ± 0.812 |
134.10 ± 0.459 |
132 – 146 a |
135.6 ± 1.478 |
135.3 ± 0.356 |
135 – 144 a |
| Total Protein (g/dL) |
4.17 ± 0.063 |
4.27 ± 0.052 |
6.1 – 7.4 a |
4.614 ± 0.230 |
3.81 ± 0.103** |
5.4 – 6.6 a |
| TRIG (mg/dL) |
32.75 ± 2.136 |
42.57 ± 3.683 |
39 – 130 a |
46.57 ± 3.077 |
54.57 ± 6.294 |
42 – 160 a |
| Urea (mg/dL) |
33.60 ± 1.503 |
37.14 ± 1.668 |
30 – 57 a |
47.43 ± 1.251 |
37.57 ± 1.232 |
30 – 42 a |
| Uric acid (mg/dL) |
1.65 ± 0.132 |
2.04 ± 0.169 |
1.2 – 2.5 a |
3.37 ± 0.377 |
2.41 ± 0.298 |
0.9 – 2.0 a |
| Bil.IND (mg/dL) |
0.08 ± 0.004 |
0.08 ± 0.003 |
0.01 – 0.01 a |
0.07 ± 0.011 |
0.08 ± 0.003 |
0.01 – 0.01 a |
| D.Bil (mg/dL) |
0.02 ± 0.004 |
0.02 ± 0.003 |
0.01 – 0.03 a |
0.03 ± 0.011 |
0.02 ± 0.003 |
0.01 – 0.03 a |
| TBil (mg/dL) |
0.10 ± 0.004 |
0.10 ± 0.003 |
0.07 – 0.09 a |
0.10 ± 0.010 |
0.10 ± 0.003 |
0.07 – 0.09 a |
| CHOL (mg/dL) | 60.60 ± 2.315 | 56.57 ± 2.599 | 55 – 79 a | 59.57 ± 3.191 | 50.14 ± 2.405 | 46 – 101 a |
FC (control female), FT (treated female), MC (control male), MT (treated male). N = 10. Data are expressed as mean ± S.D. * Indicate statistical difference between the control and treated group *p < 0.05, **p < 0.01 and ***p < 0.001 (test t). R1 (reference female); R2 (reference male); a Melo (2012).