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. 2013 Aug 5;8(8):e70637. doi: 10.1371/journal.pone.0070637

Figure 8. SporoAMA1 DIII reorganization upon ligand binding provides possible insight into signal transduction mechanisms.

Figure 8

SporoAMA1 shown in predicted organization to the T. gondii sporozoite plasma membrane, with DI and DII shown as a grey surface and DIII shown as blue cartoon with a semi-transparent blue surface, sporoRON2-D3 shown as a gold surface, and disulfides shown as yellow sticks. Dotted lines indicate extended Pro/Glu rich region between the conserved portion of DIII and the transmembrane domain (grey rectangle) that leads through to the C-terminal domain (grey oval/sphere). Left – Apo SporoAMA1. Right – SporoAMA1 bound to sporoRON2-D3.