Figure 14.

Selection of known adjacent operon pairs for training and evaluation. A: The intergenic region between two adjacent genes in an operon is doubled by extending its two ends in the two flanking genes. B: A sufficiently expressed gene is equally divided into n bins, and its central half is further equally divided into n bins. The NPKB values for each bin of a gene and of its central portion are a₁,…,a_i,…, a_j, …, a_n and b₁,…, b_i,…, b_j,…, b_n, respectively. An extended intergenic region is similarly divided by treating it as a “gene” with the intergenic region being the central portion of the “gene”. C: Distribution of PCC values between the two vectors for sufficiently expressed genes with a bin size n = 4. We choose 0.3 as the cutoff of PCC value since 60.1% of sufficiently expressed genes can be included.