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. 2013 Aug 5;8(8):e70512. doi: 10.1371/journal.pone.0070512

Table 2. Heart function in C57BL/6 and DBA/2 mice following two weeks of isoproterenol treatment.

Parameters Treatment
C57BL/6 Control C57BL/6 Isoproterenol DBA/2 Control DBA/2 Isoproterenol
Bw (g) 20.04 ± 0.33 21.75 ± 0.31 22.03 ± 0.63 21.93 ± 0.56
IVS d (mm) 0.7373 ± 0.038 0.9164 ± 0.066 # 0.8458 ± 0.043 0.9633 ± 0.04
IVS s (mm) 0.9609 ± 0.046 1.463 ± 0.091 # 1.078± 0.052 1.356 ± 0.056 #
LVID d (mm) 3.194 ± 0.079 2.997 ± 0.107 3.397 ± 0.115 3.541 ± 0.083*
LVID s (mm) 2.289 ± 0.061 1.573 ± 0.119 # 2.389 ± 0.073 2.343 ± 0.095*
LVPW d (mm) 0.9727 ± 0.061 1.44 ± 0.11 # 1.001 ± 0.062 1.439 ± 0.077 #
LVPW s (mm) 1.193 ± 0.065 1.79 ± 0.081 # 1.277 ± 0.062 1.743 ± 0.067* #
FS % 28.25 ± 1.22 47.27 ± 3.72 # 29.41 ± 1.26 33.99 ± 1.66* #
EF % 55.74 ± 1.80 78.21 ± 3.84 # 57.27 ± 1.78 63.5 ± 2.33*
Hw (mg) 71.88 ± 3.35 106 ± 6.86 # 90.35 ± 7.33 140.3 ± 7.87* #
Hw:Bw (mg/g) 3.583 ± 0.15 4.924 ± 0.331 # 3.961 ± 0.30 6.435 ± 037* #

All data are expressed as mean ± SEM

p < 0.05, student’s t-test

n = 11 (C57BL/6), 12 (DBA/2)

# indicates significant from control

*

indicates significant between strains

Abbreviations: BW, body weight; IVS, intraventricular septum; LVID, left ventricular internal diameter; LWPV, left ventricular posterior free wall; EF, ejection fraction; FS, fractional shortening; Hw, heart weight; Hw:Bw, heart weight : body weight; s, systole; d, diastole