Table 3. Prediction of the discontinuous and continuous epitopes for S. flexneri 3a OmpC.

Predicted discontinuous epitope	Score*	Predicted continuous epitope	Score
AEVYNKDGNKLDL (1–13) **	1.35	VYNKDGNKL (1–11)**	0.43
DDKSVDGD (25–32)	1.15	YFSDDKSVDGDQT (22–34)	0.63
ETQVTDQL (43–50)**	1.16	GNSAENENNSWT (62–73)	0.82
YQIQGNSAENENNSWT (58–74)	1.36	YQGKNGSPEGEGMTNNGREALRQN (149–172)	0.84
GKNGSPEGEGMTNNGREALRQNGDGV (151–174)	1.81	SSSKRTDDQNFGLNRYDERY (194–213)	0.34
KRTDDQNFGLNRYDERYIGN (197–216)	1.56	RVGNLGWANKAQNFE (248–262)	0.13
KNLGVINGRNYDD (285–297)	1.50	KGKNLGVINGRNYDD (283–297)	0.54
DDNQFTRDAG (328–337)	1.24	NKNMS (313–317)	0.10
		LLDDNQFTRDAGINTDNI (326–343)	0.42

^*the score is the average of the scores obtained for each residue.

^**inner-membrane loop.

Underlined are amino acids with their side-chains exposed to the surface of the bacterial membrane and the highest probability of contributing to the antigenic epitope.