Table 4. Synthetic epitopes and their corresponding loops in Shigella flexneri OmpC model.

Epitope*	Sequence	Loop**	Sequence
		I	SDDKSVD (24–30)
1	GNSAENENNSWT (62–73)	II	NSAEN (63–67)
		III	VVYDVTSWT (96–105)
2	EGEGMTNNGREALRQNGDGV (157–176)	IV	QNKGSPEGEGMTNNGREALRQNG (149–173)
3	GLNRYDERYIGN (205–216)	V	TDDQNFGLNRYDERYIGNG (199–217)
		VI	RVGNLG (248–253)
4	GVINGRNTDDED (288–299)	VII	NLGVINGRNYDD (286–297)
5	DDNQFTRDAG (328–337)	VIII	LDDNQFTRDAGINTDN (327–342)
6	AEVYNKDGNKLD (2–7)		intracellular loop, N-end

^*epitopes synthesized based on the highest score from continuous and discontinuous prediction method.

^** Shigella flexneri 3a OmpC loops assigned according to E. coli OmpC structure [28].