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. 2013 Aug 5;8(8):e70395. doi: 10.1371/journal.pone.0070395

Figure 9. Spatial distributions of drug exposure metrics.

Figure 9

(A) Snapshot of the intracellular maximal concentration Inline graphic, and (B) snapshot of the time integrated concentration Inline graphic from a typical simulation result from the base case. The contours delineate the viable tumor mass. (C) and (D) Plots of Inline graphic and Inline graphic from the base case as ensemble averaged (15 systems) radial distributions (black) similar to Figure 5. In addition, the vessel volume fraction is plotted as well (grey).