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. 2013 Aug 5;8(8):e70395. doi: 10.1371/journal.pone.0070395

Figure 10. Comparison of the means and STDs of the probability distribution functions (PDFs) of Inline graphic and Inline graphic.

Figure 10

These quantities are presented for different regions, where each region is associated with its own PDF using Inline graphic as index, where Inline graphic stands for the viable tumor mass, Inline graphic for tumor boundary and Inline graphic for tumor interior (see text). Spatial mean, indicated by brackets (or STD, indicated by Inline graphic) are first computed for all systems in the ensemble and then averaging over the ensemble. The error bars show respective deviations from the average within the ensemble. The meaning of the case labels is as follows: (b.c.) base case, (i) heavier drug particles, i.e. molecular mass increased by a factor of Inline graphic. (iii) neglected interstitial convection, (iv) tumor vascular permeability scaled by a factor of Inline graphic (a), Inline graphic (b), and Inline graphic (c), (v) hydraulic conductivity of interstitium scaled by a factor of Inline graphic, (vi) amount of normal lymphatics scaled by a factor of Inline graphic, (vii) presence of 10% (a) and 100% of the normal lymphatics amount in the tumor. Note that (ii) (prolonged infusions) are not shown due to the scale.