Skip to main content
. 2013 Aug 6;7:121. doi: 10.3389/fncel.2013.00121

Table 5.

Summary of neuronal population quantification, L-GABAergic cell size measurements, and of the GABAergic axon parameters.

T3 T3+ T3× T3+ Drug × T3
Mean ± s.e.m. n P# Mean ± s.e.m. n P# P* P&
L-GABA (cells/mm2)
Control 4.4 ± 0.4 60 4.4 ± 0.3 60 0.937
BDNF 4.7 ± 0.4 60 0.643 5 ± 1 50 0.253 0.138 0.255
K252a 5.1 ± 0.5 60 0.603 5.1 ± 0.5 60 0.338 0.739 0.806
Rapamycin 5.6 ± 0.4 60 0.070 4.4 ± 0.5 50 0.803 0.078 0.163
0.310 0.308
non-GABA (cells/mm2)
Control 708 ± 46 60 521 ± 29 60 0.003
BDNF 569 ± 38 60 0.029 465 ± 36 50 0.129 0.074 0.543
K252a 763 ± 53 60 0.605 553 ± 31 60 0.537 0.004 0.939
Rapamycin 967 ± 72 60 0.007 618 ± 51 50 0.326 <0.001 0.398
<0.001 0.095
GABA SOMA SIZE (μm2)
Control 308 ± 7 120 351 ± 8 120 <0.001
BDNF 308 ± 6 120 0.835 348 ± 6 120 0.572 <0.001 0.825
K252a 246 ± 4 120 <0.001 264 ± 5 120 <0.001 0.004 0.300
Rapamycin 187 ± 4 120 <0.001 241 ± 4 120 <0.001 <0.001 <0.001
<0.001 <0.001
GABA AXON LENGTH (μm/field)
Control 951 ± 40 60 715 ± 42 60 <0.001
BDNF 994 ± 42 60 0.657 762 ± 47 60 0.487 0.001 0.703
K252a 1020 ± 50 60 0.300 943 ± 38 60 <0.001 0.397 0.027
Rapamycin 676 ± 28 60 <0.001 624 ± 44 60 0.160 0.312 0.009
<0.001 <0.001
GABA BOUTONS (counts/field)
Control 47 ± 3 60 64 ± 5 60 0.009
BDNF 67 ± 3 60 <0.001 74 ± 6 60 0.309 0.836 0.038
K252a 58 ± 3 60 0.009 83 ± 3 60 <0.001 <0.001 0.174
Rapamycin 58 ± 3 60 0.003 76 ± 6 60 0.282 0.200 0.244
<0.001 0.023
MW-RST MW-RST 2w-ANOVA
ANOVA ANOVA

Statistics as in Table 4. n, number of fields analyzed per condition.