Figure 5.

CD161−CD8α+ T cells are an effector-memory population. (A) Representative FACS data comparing CCR7, CD62L, and CD54RA expression by peripheral blood CD161−CD8α+CD8β^low and CD161−CD8α+CD8β^high T cell populations as demonstrated here by a patient with chronic HBV infection. (B) Cumulative data comparing CCR7, CD62L, and CD54RA expression by peripheral blood CD161−CD8α+CD8β^low and CD161−CD8α+CD8β^high T cell populations in HCs and patients with chronic HBV, HCV, and HIV-1 infections. CD161−CD8α+CD8β^high T cell and CD161−CD8α+CD8β^low T cells represented on graphs by filled and unfilled shapes respectively. (*p < 0.05, **p < 0.001, ***p < 0.0001, Wilcoxon signed rank test).