Figure 6. S107 has no effect on atrial burst pacing-induced AF in castabin2 KO mice.
A) Representative surface ECG traces from a calstabin2 KO mouse treated with vehicle or S107. B) Prevalence of AF in calstabin2 KO mice in vehicle (n=10) and S107 treatment (n=12) groups during intra-esophageal burst pacing. C) Atrial myocytes isolated from calstabin2 KO mice were incubated with 10 µM S107 for 2 hrs before sampling for Ca2+ spark frequencies (n=13 cells in both groups).