Table 1.
Reported cases of malignant fibrous histiocytoma associated with bone necrosis
| Study | Year | Number of patients | Age/sex | Location | Radiologic findings |
|---|---|---|---|---|---|
| Galli et al. [7] | 1978 | 2 | 40/M 33/F | Proximal tibia; proximal humerus | Plain film: medullary infarct associated with soft tissue mass |
| McCarthy et al. [10] | 1979 | 35 | Mean of 34 years | Distal femur; proximal tibia | Plain film: sharply defined areas of increased density with serpiginous margins and peripheral calcifications with cortical erosion, periosteal elevation and soft tissue extension; ill-defined mass |
| Frierson et al. [5] | 1987 | 1 | 42/M | Distal femur | Plain film: sharply demarcated area of increased density with associated soft tissue mass |
| Desai et al. [1] | 1996 | 4 | 39/F 57/M 56/F 46/M | Distal femur (2); proximal tibia (1); proximal humerus (1) | Plain film: symmetric, sharply defined areas of increased density with serpiginous margins and peripheral calcifications surrounded by lytic ill-defined mass with cortical erosion, periosteal elevation, and soft tissue extension. CT: expansile, partly calcified lytic lesion exhibiting destruction of the cortex and soft tissue extension |
| Kenan et al. [8] | 1998 | 1 | 19/M | Midshaft tibia | Plain film: lytic, permeative lesion with cortical thickening, and cortical radiolucencies along the diaphyseometaphyseal section of the bone associated with medullary stenosis. MRI: cortical destructive process extending into the medullary cavity with an extraosseous mass |
| Duong et al. [4] | 2004 | 1 | 69/M | Distal tibia | Plain film: destructive lesion extending from the subchondral end plate to the metaphysis; focal lucency with marginal bone sclerosis. MRI: mass adjacent to the bone infarct extending into soft tissue with edema |
| Domson et al. [2] | 2009 | 12 | 51/F 67/M 59/F 67/M 32/M 56/F 60/M 51/F 48/M 61/F 64/F 61/F | Distal femur (5); proximal femur (1); proximal tibia (6); acetabulum (1) | Plain film: curvilinear radiodensities of the underlying mature bone infarct blending into the permeative destructive areas associated with a soft tissue mass and pathologic fracture |
M = male; F = female.