Table 2.
Study | Adequate randomization | Conceal allocation | Blinded assessor | Similar baseline | ITT analysis | Loss to followup | Detsky scores* |
---|---|---|---|---|---|---|---|
Foead et al. [14] | Yes | N/A | N/A | N/A | No | 16.7% | 15 |
Kocher et al. [28] | Yes | Yes | N/A | Yes | Yes | 0% | 19 |
Tripuraneni et al. [54] | Partial† | N/A | N/A | Yes | Yes | 0% | 14 |
Vaidya [55] | Yes | N/A | N/A | Yes | No | 9.1% | 14 |
Gaston et al. [16] | Partial† | N/A | N/A | Yes | Yes | 13.2% | 15 |
Anwar et al. [2] | Yes | N/A | N/A | N/A | No | 0% | 13 |
Maity et al. [35] | Yes | Yes | N/A | Yes | Yes | 18.8% | 18 |
* Detsky score is designed to evaluate the quality of a randomized clinical trial (maximum score 21); †quasirandomized controlled trials were considered as partial randomization (ie, patients are allocated according to known characteristics such as date of birth, hospital chart number, or day of presentation); ITT = intention-to-treat; N/A = not available.