Table 2.
Incidence of PONV*
| Parameter | Dexa-Ra (n = 135) |
Ra (n = 134) |
Significance† (p value) |
|---|---|---|---|
| Nausea | 33 (24) | 54 (40) | 0.004 |
| 0–6 hours | 29 (22) | 49 (37) | 0.028 |
| 6–24 hours | 26 (19) | 33 (25) | 1.000 (0.305) |
| 24–48 hours | 9 (7) | 9 (7) | 1.000 |
| 48–72 hours | 3 (2) | 2 (1) | 1.000 |
| Vomiting | 9 (7) | 28 (21) | 0.001 |
| 0–6 hours | 4 (3) | 28 (21) | < 0.001 |
| 6–24 hours | 5 (4) | 7 (5) | 1.000 (0.571) |
| 24–48 hours | 1 (1) | 1 (1) | 1.000 |
| 48–72 hours | 0 (0) | 0 (0) | – |
PONV = postoperative nausea and vomiting; * data presented as number (percentage) of patients who experienced nausea or vomiting; Dexa-Ra = dexamethasone and ramosetron; RA = ramosetron; †p values in parentheses are the uncorrected values before Bonferroni analysis. The incidence of vomiting during 48 to 72 hours was not statistically analyzed.