Figure 1.

Effects of triptolide and anti-rheumatic drugs on the viability of rheumatoid synovial fibroblasts (RSF). Cells were incubated with triptolide (closed diamond), bucillamine (closed triangle), methotrexate (closed circle), D-penicillamine (open triangle), sodium aurothiomalate (open diamond), or sulphasalazine (open circle) for 24 h. Then viability was measured by the WST-1 assay and calculated as a percentage of the control value (untreated cells). Data are the mean ± S.D. for triplicate cultures and representative results from 6 independent experiments are shown.