Skip to main content
. 2013 Jul 2;9:679. doi: 10.1038/msb.2013.35

Figure 3.

Figure 3

AARS-2 knockdown extends longevity independent of reduced reproduction, but dependent on daf-16. Representative survival curve of N2 (A) and daf-16(mu86) (B) nematodes fed from L4 with either control RNAi (black lines) or RNAi targeting aars-2, alanyl-tRNA synthetase (red). All experiments were carried out at 25°C with n⩾30 animals per assay. Statistical differences were calculated by log-rank (Mantel–Cox) test. See Supplementary Tables IV and V for the overview of all performed lifespan assays. (C) Brood size experiments of N2 nematodes fed on control RNAi or RNAi targeting aars-2, pab-1, or snr-2. Bar graphs represent average offspring per nematode and N⩾14 per condition. See Supplementary Table VI for more detail.