Figure 2.

Hierarchical clustering of tumors from different stages of colorectal cancer. The hierarchical clustering is based on chromosome aberrations of all chromosome arms. Chromosome arms 13p, 14p, 15p, 21p, 22p, and chromosome Y, due to high content of heterochromatin, were excluded from the cluster analysis. The chromosome arms are given in the right dendogram (gains in green and losses in blue). Each tumor sample is depicted and coded (white – primary carcinomas; yellow – local recurrence; green – peritoneal carcinomatoses; red – liver metastases) at the top of the dendogram. Each row represents the alterations from a separate chromosome arm over all tumor samples, and each column represents all changes in each tumor.