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. Author manuscript; available in PMC: 2013 Aug 6.
Published in final edited form as: J Urol. 2013 Feb 27;190(2):757–764. doi: 10.1016/j.juro.2013.02.090

Figure 3.

Figure 3

Antisense OND mediated suppression of AA induced NGF protein expression in urothelium (A) and detrusor (B), and NGF mRNA expression in whole bladder (C). AA exposure caused significant increase in NGF in sham treated group (Sham) vs untreated controls. NGF antisense OND significantly blunted NGF increase vs sham treated group. Data points represent NGF values of individual rats around mean (horizontal line) of each group. Significant decrease was noted in whole bladder mRNA levels of rats treated with NGF antisense OND complexed with liposomes vs levels in controls (C). Normalized NGF levels were compared by ANOVA followed by Tukey test. Asterisk indicates p <0.05.