. 2013 Apr 15;12(8):2048–2059. doi: 10.1074/mcp.M112.026716

Table I. SILAC ratios for the H3 K79 peptide EIAQDF⁷⁹K(Me_0–3)TDLR across all 44 yeast mutants. Each ratio is the average of three replicates. A t-test was performed between the wild type and each mutant. Peptide ratios with a p value ≤ 0.05 are reported as significant.

	H3 K79Me₀		H3 K79Me₁			H3 K79Me₂			H3 K79Me₃
	Average	Std. Dev	Average	Std. Dev	p value	Average	Std. Dev	p value	Average	Std. Dev	p value
WT2	1.15	0.14	1.12	0.22	1.0E+00	0.98	0.16	1.0E+00	0.90	0.03	1.0E+00
H2A K4R	1.17	0.22	1.42	0.05	4.3E-01	1.22	0.09	6.3E-01	0.80	0.09	2.8E-01
H2A K4Q	0.60	0.07	0.88	0.09	5.2E-03	1.05	0.13	1.0E-02	1.16	0.06	1.0E-02
H2A K7R	0.64	0.02	0.91	0.09	1.3E-02	1.13	0.05	9.8E-06	1.14	0.02	1.4E-03
H2A K7Q	0.89	0.07	1.44	0.01	3.7E-03	1.33	0.05	2.2E-02	0.74	0.01	6.9E-01
H2A K21R	0.93	0.08	0.97	0.03	2.2E-01	1.07	0.06	2.0E-02	0.89	0.05	8.4E-02
H2B K6R	0.83	0.09	1.05	0.11	4.9E-02	1.03	0.11	7.8E-02	1.16	0.13	2.8E-02
H2B K6Q	1.00	0.25	0.97	0.05	8.5E-01	1.03	0.03	3.5E-01	1.09	0.09	2.7E-01
H2B S10E	1.42	0.44	1.28	0.39	9.9E-01	1.25	0.33	1.0E-01	1.25	0.29	2.3E-01
H2B S10A	1.05	0.09	1.00	0.06	9.5E-01	0.94	0.03	5.5E-01	1.09	0.02	4.8E-02
H2B K11R	1.03	0.10	1.09	0.13	2.4E-01	1.02	0.04	8.9E-02	0.79	0.06	9.0E-01
H2B K11Q	1.13	0.11	1.19	0.16	7.9E-01	0.92	0.15	5.9E-01	1.06	0.13	4.6E-01
H2B K16R	0.87	0.12	1.10	0.02	1.2E-01	1.18	0.08	1.3E-01	1.04	0.07	7.5E-02
H2B K16Q	0.42	0.06	0.59	0.11	2.7E-02	0.67	0.17	2.9E-02	0.52	0.13	3.4E-02
H2B K17R	1.02	0.11	1.64	0.22	4.5E-03	1.51	0.09	2.9E-03	1.08	0.07	3.7E-02
H2B K17Q	0.82	0.04	0.95	0.06	8.9E-02	1.07	0.05	2.1E-02	0.93	0.09	1.5E-02
H2B K21R	0.57	0.21	1.13	0.05	1.9E-01	1.29	0.03	1.7E-01	0.96	0.06	1.8E-01
H2B K21Q	0.65	0.08	1.09	0.09	1.6E-03	1.25	0.10	9.5E-04	0.96	0.05	2.2E-03
H2B K22R	0.71	0.02	1.31	0.07	4.6E-04	1.33	0.03	7.2E-06	0.82	0.01	1.6E-02
H2B K22Q	0.96	0.48	0.77	0.15	6.3E-01	0.70	0.14	5.6E-01	0.55	0.13	8.3E-01
H2B K123R	1.39	0.12	0.69	0.05	1.5E-02	0.02	0.00	7.9E-04	0.01	0.00	6.5E-03
H2B K123Q	1.87	0.43	2.98	1.07	7.7E-02	0.35	0.10	1.6E-04	0.01	0.00	6.4E-03
WT1	0.89	0.09	1.00	0.06	1.0E+00	0.98	0.12	1.0E+00	0.91	0.13	1.0E+00
H3 K4A	0.83	0.07	1.22	0.26	1.4E-01	1.42	0.36	1.2E-01	1.50	0.28	1.4E-02
H3 K9R	0.85	0.07	0.88	0.12	3.3E-01	0.79	0.12	2.0E-01	0.92	0.20	5.8E-01
H3 T11A	1.03	0.03	1.02	0.05	2.1E-01	1.00	0.08	2.9E-01	1.20	0.09	1.4E-01
H3 K14R	1.06	0.18	1.03	0.21	1.4E-01	0.97	0.19	1.8E-01	1.06	0.04	9.2E-01
H3 K18R	1.10	0.20	1.08	0.18	2.3E-01	0.96	0.17	1.3E-01	1.02	0.11	8.0E-01
H3 K23R	1.00	0.09	1.06	0.08	5.9E-01	0.98	0.05	3.4E-01	1.06	0.05	5.1E-01
H3 K36R	0.85	0.10	0.88	0.02	4.3E-01	1.09	0.09	1.8E-01	1.18	0.03	8.9E-02
H3 K36A	0.90	0.08	0.77	0.02	5.6E-02	0.81	0.03	1.4E-01	1.09	0.02	8.1E-02
H3 K56R	0.84	0.04	0.99	0.11	8.7E-01	0.96	0.02	5.8E-01	1.15	0.06	2.8E-02
H4 K5R	0.91	0.12	1.28	0.25	1.2E-01	1.09	0.24	9.2E-01	0.92	0.17	5.9E-01
H4 K5Q	0.91	0.14	0.95	0.08	5.0E-01	0.90	0.09	4.5E-01	0.90	0.11	8.8E-01
H4 K8R	0.95	0.08	1.21	0.28	4.0E-01	1.17	0.32	4.6E-01	0.98	0.14	9.4E-01
H4 K8Q	1.17	0.20	1.43	0.09	6.1E-01	1.25	0.11	8.6E-01	0.87	0.13	4.3E-01
H4 K12R	1.33	0.21	1.37	0.35	2.3E-01	1.29	0.23	5.1E-01	0.88	0.23	3.6E-01
H4 K12Q	0.94	0.14	1.36	0.15	3.7E-02	1.32	0.14	5.1E-02	0.55	0.07	1.2E-02
H4 K16R	1.08	0.11	1.37	0.12	5.1E-01	1.30	0.39	4.2E-01	0.94	0.09	3.9E-01
H4 K16Q	1.23	0.11	2.46	0.17	7.5E-03	1.59	0.07	1.2E-01	0.44	0.06	2.6E-03
H4 K31R	0.62	0.07	1.03	0.10	6.5E-02	1.12	0.12	5.9E-02	0.94	0.08	1.4E-02
H4 K31Q	0.77	0.14	0.74	0.10	1.3E-01	0.83	0.11	9.9E-01	1.01	0.15	3.5E-02
H4 K79R	0.95	0.08	0.98	0.07	7.1E-01	0.99	0.07	9.5E-01	1.10	0.07	1.8E-01
H4 K79A	0.81	0.02	0.94	0.06	8.7E-01	1.10	0.02	6.4E-02	1.05	0.02	3.7E-02
H4 K91Q	0.46	0.17	0.53	0.16	4.4E-01	0.61	0.19	3.9E-01	0.62	0.16	9.8E-02

Table I. SILAC ratios for the H3 K79 peptide EIAQDF79K(Me0–3)TDLR across all 44 yeast mutants. Each ratio is the average of three replicates. A t-test was performed between the wild type and each mutant. Peptide ratios with a p value ≤ 0.05 are reported as significant.

Table I. SILAC ratios for the H3 K79 peptide EIAQDF⁷⁹K(Me_0–3)TDLR across all 44 yeast mutants. Each ratio is the average of three replicates. A t-test was performed between the wild type and each mutant. Peptide ratios with a p value ≤ 0.05 are reported as significant.