Table 2.

Results of population-based studies indicating higher incidence of APL and higher early death rate with increasing age

Author (year) [reference]	Age groups (years)	No. of pts	Incidence per 100,000	Early death	p value	Outcome		p value
Park (2011) [28]				Probability of ED (%)		Survival rate (%)
						1 year	3 years
	<35	433	0.13	12.3	<0.001	81.2	76.3	<0.001
	35–54	463	0.26	16.0		75.6	72.0
	≥54	502	0.42	24.2		53.2	46.4
	Total	1,400
Chen (2012) [29]				Probability of ED (%)		Cumulative relative survival
						1 year	5 years
	<20	149	0.06	n.r.		0.79	0.52
	20–39	372	0.19	n.r.		0.71	0.57
	40–59	427	0.22	n.r.		0.67	0.57
	≥60	449	0.36	n.r.		0.38	0.24
	Total	1,397
Lehmann (2011) [27]				Rate of ED (%)		Survival rate (%)a
						1 year	5 years
	<40	28		19		82	82
	40–59	37		16		83	74
	≥60	40		50		37	24
	Total	105

n.r. not reported, pts patients, ED early death

^aApproximate values extracted from survival curves