Figure 3.

Nasal nitric oxide (nNO) and ciliary beat frequency (CBF) association in patients and healthy control subjects. (a) nNO was measured in healthy control subjects (310 ± 76 nl/min; n = 35), patients with pulmonary nontuberculous mycobacteria (PNTM) (237 ± 74 nl/min; n = 52), and patients with primary ciliary dyskinesia (PCD) (26 ± 24 nl/min; n = 7). Patients with PNTM had significantly lower nNO than healthy control subjects but not in the range of PCD (P < 0.0001; ANOVA). (b) CBF (Hz) is plotted as a function of nNO concentration (nl/min). A positive correlation was found between CBF and nNO concentration (0.31 Spearman’s rho, P < 0.01; linear regression, y = 0.005x + 7.63 Hz) for all patients. Data are presented as means; error bars show SD. **P < 0.005.