Table 4. Univariate Analysis Of Medical And Surgical Risk Factors Associated With A Creatine Kinase > 5 ULN.

Risk factor	CK < 5 ULN (96 patients)	CK > 5 ULN (18 patients)	p-value
Ischaemic heart disease	69 (72%)	12 (67%)	0.778*
Diabetes	37 (39%)	4 (22%)	0.284*
Serum creatinine > 180 μmol.l-1	19 (20%)	8 (44%)	0.030†
Troponin positive	18 (19%)	7 (39%)	0.058†
Statin therapy	29 (30%)	2 (11%)	0.095†
Supra-inguinal surgery	19 (20%)	3 (17%)	0.758
Embolectomy and/or fasciotomy	9 (9%)	4 (22%)	0.116†
Duration of surgery	100 (68–145)	85 (64–138)	0.306‡

Values are number (proportion) or median (range).

CK creatine kinase; ULN upper limit of normal

*Fisher’s exact test; ^†Pearson’s Chi-square test; ^‡Mann-Whitney U-test