Table 1. Physiologic parameters.
Baseline SBP (mm Hg) | Day 7 SBP (mm Hg) | Before killing SBP (mm Hg) | Weight loss after tMCAO (g) | |
---|---|---|---|---|
Sham | 177.5±5.6 | 175.3±5.1 | 180.7±5.8 | 6.83±2.7 |
tMCAO | 173.2±3.8 | 177.8±4.2 | 175.4±4.5 | 15.22±3.0 |
tMCAO+CAVGFP | 171.4±4.3 | 181.3±4.5 | 186.6±3.3 | 12.59±1.7 |
tMCAO+SP600125 | 179.3±3.1 | 179.3±2.8 | 179.3±4.2 | 18.11±3.5 |
tMCAO+CAVNgb | 174.7±4.2 | 182.8±2.8 | 177.7±4.1 | 13.13±2.5 |
tMCAO+CAVNgb+SP600125 | 173.5±5.4 | 176.8±4.3 | 182.6±2.9 | 18.11±3.5 |
CAVGFP, canine adenovirus type 2 vector overexpressing green fluorescent protein; Ngb, neuroglobin; SBP, systolic blood pressure; tMCAO, transient middle cerebral artery occlusion.
SBP measured 3 days before (baseline) and 7 and 14 days after tMCAO (before killing) and the change in body weight over the corresponding period. Data presented as mean±s.e.m, n=6 to 9.