Figure 7.

Upregulation of CXCR4 in the infarct border zone in stroke patients. (A) Levels of CXCR4 in unaffected brain tissue of the noninjured hemisphere (lanes 1 and 2), infarct core (lanes 3 and 4), and proximal peri-infarct area (lanes 5 and 6) after clinical stroke. (B) Levels of CXCR4 in the infarct core (lanes 1 and 2) and old infarcts (lanes 3 and 4) after clinical stroke. (C) Values are means±s.d. and were obtained from the indicated brain regions of six patients and were calculated as percentage of β-actin expression. *P<0.05 versus noninfarcted control tissue of the contralateral hemisphere (contr) and old infarct tissue (infarcted areas older than 2 months). Statistical analysis was performed by one-way analysis of variance and Bonferroni correction. M, protein marker.