Table 4. Double-blind, placebo-controlled trial of cATSCs on five atopic dogs.
|
Atopy |
||||
|---|---|---|---|---|
| Normal (n=5) | PBS (n=5) | cATSC Ex. (n=5) | P-value | |
| Clinical evaluation score | — | 5.2±1.64 | 4.2±0.84 | <0.05 |
| Skin hydration | 16.2±3.03 | 6.27±1.08 | 12.35±3.62 | <0.05 |
| TEWL | 13.38±0.98 | 42.16±12.72 | 27.48±6.34 | NS |
| Skin pH | 8.44±0.52 | 8.37±0.47 | 8.34±0.48 | NS |
Note: P-values are ANOVA.
After application of cATSCs extract, clinical symptom of AD was ameliorated in their clinical evaluation score and skin hydration was improved than PBS placebo.