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. Author manuscript; available in PMC: 2013 Aug 6.
Published in final edited form as: Toxicol Pathol. 2008 Dec 15;37(1):47–51. doi: 10.1177/0192623308329476

Figure 1. Inverse linear relationship between caloric intake and lifespan in mice.

Figure 1

C3B10F1 females were individually housed and placed on controlled diets (115kcal/wk, 85kcal/wk, 50 kcal/wk and 40kcal/wk) from weaning (n =49, 57, 71, 60 respectively). Animals with the highest caloric intake died earliest and survival improved with increased caloric restriction.