Table 2.
—Frequencies of Demographic Characteristics Among Classes in the Three-Class Model
| Characteristics | Class 1 (n = 197) | Class 2 (n = 25) | Class 3 (n = 139) | P Valuea |
| Recipient | ||||
| Recipient age, y | 52.9 ± 12.3 | 51.5 ± 14.6 | 53 ± 12.0 | .41 |
| Native disease | .45 | |||
| COPD | 50 (26) | 3 (12) | 40 (29) | |
| CF | 17 (9) | 5 (20) | 16 (12) | |
| IPF | 81 (41) | 13 (52) | 60 (43) | |
| PPH | 11 (6) | 1 (4) | 8 (6) | |
| Sarcoid | 17 (9) | 1 (4) | 6 (4) | |
| Other | 20 (10) | 2 (8) | 9 (6) | |
| Female recipient | 92(47) | 10 (40) | 61 (44) | .76 |
| Prior pregnancy | 73 (79) | 6 (60) | 41 (67) | .15 |
| Recipient race | .29 | |||
| White | 152 (77) | 18 (72) | 110 (79) | |
| Black | 32(16) | 6 (24) | 18 (13) | |
| Hispanic | 4 (2) | 1 (4) | 9 (6) | |
| Asian | 6 (3) | 0 (0) | 1 (< 1) | |
| Other | 3 (2) | 0 (0) | 1 (< 1) | |
| BMI recipient | 26.8 ± 5.5 | 24.6 ± 5.0 | 26.1 ± 4.8 | .25 |
| LAS (n = 312) | 46.9 ± 15.9 | 47.6 ± 14.2 | 45.7 ± 15 | .65 |
| Donor | ||||
| Female donor | 91(46) | 14 (56) | 56 (41) | .28 |
| Donor age, y | 35.6 ± 14.6 | 27.8 ± 10.4 | 35.7 ± 13.2 | .08 |
| Donor race | .45 | |||
| White | 128 (65) | 17 (68) | 96 (69) | |
| Black | 43 (22) | 6 (24) | 20 (15) | |
| Hispanic | 17 (9) | 2 (8) | 18 (13) | |
| Other | 9 (5) | 0 (0) | 5 (4) | |
| Donor ventilation days | .73 | |||
| One | 58 (30) | 6 (24) | 31 (22) | |
| Two | 54 (27) | 6 (24) | 43 (31) | |
| Three | 36 (19) | 7 (28) | 31 (22) | |
| Four | 49 (25) | 6 (24) | 34 (24) | |
| Donor smoking | 100 (51) | 6 (24) | 61(44) | .03 |
| Donor mode of death | .02 | |||
| Trauma | 79 (40) | 10 (40) | 61(44) | |
| Stroke | 83 (42) | 9 (36) | 60 (43) | |
| Anoxia | 10 (5) | 3 (12) | 15 (11) | |
| Other | 25 (13) | 3 (12) | 3 (2) | |
| Operative | ||||
| Bilateral transplant | 135 (69) | 15 (60) | 91 (66) | .64 |
| CPB | 120 (61) | 10 (40) | 64 (46) | .01 |
| Intraoperative nitric oxide | 122 (62) | 16 (64) | 88 (63) | .95 |
| Intraoperative crystalloids, mean ± SD, mL | 1,056.3 ± 1,593 | 1,550 ± 2,114 | 1,547.8 ± 2,083.2 | .002 |
| Reperfusion Fio2, mean ± SD | 67.1 ± 28.7 | 71.8 ± 26.4 | 66.7 ± 29.8 | .73 |
| Tidal volume, mean ± SD, mL/kg | 7.0 ± 3.2 | 8.0 ± 2.6 | 7.0 ± 2.6 | .05 |
| PRBC, mean ± SD, mL | 1,142.3 ± 1,547 | 694 ± 983.1 | 914.1 ± 1,255.5 | .003 |
| PAP, mean ± SD, mm Hg | 34.5 ± 16.4 | 29.7 ± 12.9 | 29 ± 12 | .001 |
Data given as No. (%) unless otherwise indicated. LAS = lung allocation score; PAP = pulmonary artery pressure at the time of transplantation. See Table 1 legend for expansion of other abbreviations.
a
P values were calculated using χ2 and t tests.