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. 2013 Aug;144(2):638–650. doi: 10.1378/chest.12-2114

Table 2.

—Clinical Features and Risk Factors Distinguishing PAH From PH Due to HFpEF

PAH6 PH Due to HFpEF
Family history Older age38,65
Use of anorexigens, amphetamines Systemic hypertension45,65
Connective tissue disease; systemic sclerosis, SLE, MCTD Diabetes45,65
HIV Coronary artery disease45,65
Liver disease, portal hypertension Atrial fibrillation38
Congenital heart disease Obesity38,45,65
Schistosomiasis Hyperlipidemia45
Orthopnea, PND
Exaggerated increase in BP with exercise66
ECG: right axis, RAE, RVH67,68 ECG: left axis, LAE, LVH69

LAE = left atrial enlargement; LVH = left ventricular hypertrophy; MCTD = mixed connective tissue disease; PND = paroxysmal nocturnal dyspnea; RAE = right atrial enlargement; RVH = right ventricular hypertrophy; SLE = systemic lupus erythematosus.