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Sequence alignment of variable region of mAbs D44.1 and F10.6.6. Amino acid sequences of VH D44.1, VH F10.6.6, VL D44.1, and VL F10.6.6 (GenBank accession no. AY277254). VL F10.6.6 was cloned and sequenced as described (23). Assignment of antibody CDRs follows the AbM definition, based on sequence variability (Kabat definition, refs. 41 and 42) and the location of the structural loop regions (Chothia definition, ref. 43). CDR residues are underlined in both sequences.
