Figure 1.

The change in the serum testosterone. The mean serum testosterone was 0.14 ng ml⁻¹ at the baseline level, and it decreased to a nadir level of 0.06 ng ml⁻¹ after the ketoconazole therapy. When the PSA progressed, the serum testosterone increased to 0.13 ng ml⁻¹. The red line denotes the change in serum testosterone, and the minor axis shows the 95% confidence interval for serum testosterone. PSA, prostate-specific antigen.