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. 2012 May 14;14(5):766–772. doi: 10.1038/aja.2012.27

Table 3. Linear regression analysis of joint relationship of genotypes and maternal urinary phthalate with genital distance measures (adjusted for center, age and infant weight percentile), Study for Future Families II, 1999–2005.

  Genotype Measure Phthalate Phthalate* genotype interaction term coefficient (95% CI) P value
rs2077647 AA or AG AGD Sum DEHP Metabolites (MEHP/MEOHP/MEHHP) −1.3 (−6.0, 3.4) 0.58
      MEP −2.0 (−4.8, 0.8) 0.16
      MBP 0.1 (−4.4, 4.5) 0.97
rs10475 TT or TC ASD Sum DEHP metabolites (MEHP/MEOHP/MEHHP) −0.8 (−4.2, 2.7) 0.67
      MEP 0.01 (−2.1, 2.1) 0.99
      MBP −0.7 (−4.2, 2.9) 0.71

Abbreviations: AGD, anogenital distance; ASD, anoscrotal distance; MBP, mono-butyl phthalate; MEHHP, mono-(2-ethyl-5-hydroxyhexyl) phthalate; MEHP, mono(2-ethylhexyl) phthalate; MEOHP, mono-(2-ethyl-5-oxohexyl) phthalate; MEP, mono-ethyl phthalate.

*Refers to a statistical interaction term to examine how phthalate modify the relationship between genotype and outcome.