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Morphology of F-actin observation in 5637 cell. (a) pdelta Np63-shRNA group; (b) pdelta Np63-cRNA group; (c) PBS group. The protein level of F-actin in pdelta Np63-shRNA is obviously increased (a). But in pdelta Np63-cRNA and PBS groups, the F-actin is diffusion, brightness of microfilament is lower, cell polarity disappears, and cell arrangement is crumbly and irregular (b, c). PBS, phosphate-buffered saline; shRNA, short hairpin RNA.
