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. 2009 Jan 12;11(2):240–251. doi: 10.1038/aja.2008.30

Figure 6.

Figure 6

Amino acid sequence alignment of human members of the RNase A superfamily. The alignment was generated by CLUSTAL W (version 1.83). Gaps are indicated by dashes. The starting residues of the mature RNase A proteins are underlined. The conserved CKXXNTF motif are boxed, with three catalytic residues indicated by “↓” and eight conserved cysteines indicated by “♦”. “#”, the residues in that column are identical in all sequences. “*”, conserved substitution; “:”, semi-conserved substitution. GenBank accession numbers: RNase 1 (NP_937878), RNase 2 (NP_002925), RNase 3 (NP_002926), RNase 4 (NP_919411), RNase 5 (NP_001136), RNase 6 (NP_005606), RNase 7 (NP_115961), RNase 8 (NP_612204), RNase 9 (AAQ02792), RNase 10 (AAV87183), RNase 11 (AAV87184), RNase 12 (AAV87185), RNase 13 (AAV87186).