Fig. 3.

Degradation of 3OC12-HSL by cultured mammalian cells. Shown are the amounts of C4-HSL (gray bars) and 3OC12-HSL (black bars) remaining after a 1-h exposure to various mammalian cells in culture. Cell lines included are A549 cells, established from human bronchoalveolar carcinoma, CaCo-2 from human colon carcinoma, MDCK from canine kidney, CHO from Chinese hamster ovary, 293T from human embryonic kidney, HeLa from human cervix, COS-7 from monkey kidney, and primary cultures of human lung fibroblasts (HLF). Data are means ± SEM (n = 8 replicates).