Figure 1.
Effects of MFME on prostate weight. The rat model of BPH was created by giving rats testosterone injections for 4 weeks after castration. Castration: corn oil injection (s.c.)+oral administration of PBS; BPH: testosterone (s.c.) injection+oral administration of PBS; MFME: oral administration of MFME (200 mg kg−1)+testosterone (s.c.) injection; finasteride: oral administration of finasteride (10 mg kg−1)+testosterone (s.c.) injection. MFME or finasteride treatment was performed 1 h before testosterone injection. Values are expressed as mean±s.d. *P<0.05, compared with castration group; #P<0.05, compared with BPH group. BPH, benign prostate hyperplasia; MFME, Melandrium firmum methanolic extract; PBS, phosphate-buffered saline.