Table 3. Some of the genes most strongly regulated and highly expressed in S-AR−/y mice, but not in TM4/AR cells.
Symbol | Description | TPM | ||||
---|---|---|---|---|---|---|
WT | S-AR−/y | TM4-1 | TM4-2 | TM4-3 | ||
Spata3 | Spermatogenesis associated 3 | 745.54 | 1.36 | — | — | — |
Hils1 | Histone H1-like protein in spermatids 1 | 2527.18 | 4.89 | 0 | 0 | 0.56 |
Spem1 | Sperm maturation 1 | 1309.14 | 2.72 | — | — | — |
Spatc1 | Spermatogenesis and centriole associated 1 | 397.57 | 1.09 | — | — | — |
Spata19 | Spermatogenesis associated 19 | 869.26 | 2.99 | — | — | — |
Spaca3 | Sperm acrosome associated 3 | 67.38 | 0.27 | — | — | — |
Txndc2 | Thioredoxin domain containing 2 (spermatozoa) | 191.91 | 0.81 | 0 | 0 | 0.28 |
Gapdhs | Glyceraldehyde-3-phosphate dehydrogenase, spermatogenic | 1480.03 | 6.25 | 0.26 | 0 | 0 |
Odf3l1 | Outer dense fiber of sperm tails 3-like 1 | 217.25 | 1.09 | — | — | — |
Spata9 | Spermatogenesis associated 9 | 46.36 | 0.27 | 0.26 | 0.28 | 0 |
Spata18 | Spermatogenesis associated 18 | 197.3 | 1.36 | — | — | — |
Odf3b | Outer dense fiber of sperm tails 3B | 38.54 | 0.27 | — | — | — |
Spam1 | Sperm adhesion molecule 1 | 35.58 | 0.27 | — | — | — |
Txndc3 | Thioredoxin domain containing 3 (spermatozoa) | 32.07 | 0.27 | — | — | — |
Spert | Spermatid associated | 117.52 | 1.09 | — | — | — |
Spata20 | Spermatogenesis associated 20 | 462.26 | 6.79 | — | — | — |
Spaca4 | Sperm acrosome associated 4 | 220.75 | 3.26 | — | — | — |
Catsper3 | Cation channel, sperm associated 3 | 48.79 | 0.81 | 0 | 0 | 0.28 |
Izumo1 | Izumo sperm-egg fusion 1 | 73.31 | 1.36 | — | — | — |
Spaca1 | Sperm acrosome associated 1 | 146.36 | 3.26 | — | — | — |
Abbrevations: TPM, normalized expression of gene; SAR–/y, S-AR–/y mice testis; TM4-1, TM4/AR cells; TM4-2, TM4/AR cells with AR-cDNA transient transfected; TM4-3, TM4/AR cells with AR-cDNA transient transfected and T treatment; WT, wild-type mice testis; –, no signal.