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. 2004 Feb 26;101(10):3650–3655. doi: 10.1073/pnas.0306587101

Fig. 5.

Fig. 5.

Depolarization-evoked dopamine release and tyrosine hydroxylase content of tPA-/- mice. (A) High KCl (60 mM)-induced dopamine release in the NAcc of wild-type and tPA-/- mice. The lack of tPA significantly attenuated the depolarization-evoked dopamine release in the NAcc [F(1, 10) = 6.846, P < 0.05]. (B) Immunoblot analysis of tyrosine hydroxylase of tPA-/- mice. There were no differences in the protein content of tyrosine hydroxylase in the lower midbrain and NAcc between tPA-/- and wild-type mice. Values indicate means ± SE (n = 6 for A, and n = 4 for B).