FIG 5 .

Both GAS and GBS can respond to nonnative synthetic SHP-C8 peptides predicted to be produced by other species. SHP-null GAS reporter strain BNL177 (A) and GBS reporter strain BLC101 (pSar110) (B) are both induced by sSHP2-C8, sSHP3-C8, and sSHPporc-C8 but not by sSHP2-rev-C8. sSHPporc-C8 induces both reporters approximately 10-fold less than sSHP2-C8 or sSHP3-C8. Data are shown as a function of relative light units (CPS/OD₆₀₀) versus OD₆₀₀. Each graph is representative of at least 3 biological replicates.