Table 2. Effects of ZOLP and L-655,708 on mIPSCs from Swiss White mice.
Group | n | Frequency, Hz | Amplitude,.pA | Rise, ms | Q, pA·ms | Decay, ms |
---|---|---|---|---|---|---|
Control | 9 | 4.3 ± 1.0 | 43.2 ± 1.5 | 2.0 ± 0.1 | 1004.6 ± 71.8 | 21.6 ± 5.8 |
ZOLP (20 nM) | 9 | 5.4 ± 1.5 | 44.3 ± 3.2 | 2.2 ± 0.2 | 1116.2 ± 115.2 | 23.1 ± 1.9 |
ZOLP (100 nM) | 8 | 4.7 ± 1.6 | 44.6 ± 3.7 | 2.1 ± 0.1 | 1324.8 ± 140.8* | 29.6 ± 2.7* |
Control | 7 | 1.9 ± 0.6 | 44.5 ± 6.7 | 2.2 ± 0.2 | 902.3 ± 76.1 | 18.5 ± 1.7 |
L-655,708 (50 μM) | 7 | 2.6 ± 0.6 | 43.8 ± 6.7 | 2.4 ± 0.4 | 944.2 ± 111.1 | 18.6 ± 1.7 |
*, P < 0.05 vs. control.