FIG 5 .

Noniron metalloporphyrins inhibit staphylococcal growth. (A) Growth of S. aureus in the presence of increasing concentrations of GaPPIX or ZnPPIX. The growth of the strains was monitored over time by measuring optical density at 600 nm. The average from three independent experiments is shown. Error bars represent one standard deviation from the mean. (B) Aerobic (+O₂) or anaerobic (−O₂) growth of S. aureus in the presence of increasing concentrations of GaPPIX or ZnPPIX. Growth was monitored as the optical density at 12 h and compared to that of cells grown in the absence of the noniron PPIXs. The average from three independent experiments is shown. Error bars represent one standard deviation from the mean. (C) S. aureus was grown in the absence or presence of 1 mM 2,2′-dipyridyl (±DIP) and 0.1 µM GaPPIX or ZnPPIX. Growth was monitored as the optical density at 12 h and compared to that of cells grown in the absence of the noniron PPIXs. The average from three independent experiments is shown. Error bars represent one standard deviation from the mean.