TABLE 3.
Regimen | % (Proportion) of Mice Relapsing after Treatment for: |
||
---|---|---|---|
5 mo | 6 mo | 7 mo | |
2 mo RHZ + RH |
23 (7/30) |
0 (0/30) |
Not done |
2 mo MEtZA + MEtZ |
97 (28/29) |
59 (17/29) |
20 (6/30) |
2 mo LEtZA + LEtZ | 100 (26/26) | 79 (23/29) | 38 (11/29) |
Definition of abbreviations: A = amikacin; Et = ethionamide; H = isoniazid; L = levofloxacin; M = moxifloxacin; R = rifampin; Z = pyrazinamide.
Relapse was defined by a positive culture upon plating the entire lung homogenate harvested 3 mo after completing the indicated duration of treatment.