Figure 1.

Interrelations of LPS-induced cytokine production in early-life and childhood asthma. See Methods for definitions of grouped variables of cytokines from LPS-stimulated blood mononuclear cells showing persistence of production from birth to 3 months. The “any low” group (subjects with low/low, low/missing, and missing/low values) is compared with the “high/high” group (subjects with high values at both cord and 3 mo). The “high/missing” group is excluded from this analysis. Group sizes are given in the bars. Childhood asthma is defined as physician-diagnosed asthma between ages 2 and 9. The P values are based on chi-square. TNF = tumor necrosis factor.