Risk ratios for diabetes associated with CCBs, compared to other antihypertensive drugs.
Notes: Boxes, estimated risk ratios (RRs); bars, 95% CI. Diamonds, fixed-effects model RRs; width of diamonds, pooled CIs. The size of each box is proportional to the weight of each study in the meta-analysis.
Abbreviations: AASK, African American Study of Kidney diseases and hypertension; ACEI, Angiotensin-Converting Enzyme Inhibitor; ALLHAT, Antihypertensive and Lipid Lowering to prevent Heart Attack Trial; ARB, angiotensin-receptor blocker; ASCOT-BPLA, Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm; CASE-J, Candesartan Antihypertensive Survival Evaluation in Japan; CCB, calcium channel blocker; INSIGHT, International Nifedipine; GITS Study, Intervention as a Goal in Hypertension Treatment Study; INVEST, International Verapamil-Trandolapril Study; NICS-EH, National Intervention Cooperative Study in Elderly Hypertensives; NORDIL, Nordic Diltiazem study; M-H, Mantel–Haenszel; STOP-2, Second Swedish Trial in Older Patients with hypertension-2; VALUE, Valsartan Antihypertensive Long-term Use Evaluation.