Table 4. The frequencies of each genotype in the controls and the subgroups of infertile patients.
Genotype | Controls (n = 101) | Infertile patients |
|||
---|---|---|---|---|---|
Overall (n = 274) | vs. controls | Varicocele patients (n = 72) | vs. controls | ||
GSTM1 | |||||
Null | 52.5% (53) | 58.0% (159) | 62.5% (45) | ||
wt | 47.5% (48) | 42.0% (115) | NS | 37.5% (27) | NS |
GSTT1 | |||||
Null | 50.5% (51) | 46.0% (126) | 47.2% (34) | ||
Wt | 49.5% (50) | 54.0% (148) | NS | 52.8% (38) | NS |
MnSOD | |||||
Ala/Ala | 2.0% (2) | 0.7% (2) | 0.0% (0) | ||
Ala/Val | 14.8% (15) | 21.2% (58) | NS | 18.1% (13) | NS |
Val/Val | 83.2% (84) | 78.1% (214) | 81.9% (59) | ||
NQO1 | |||||
Pro/Pro | 36.6% (37) | 39.1% (107) | 34.7% (25) | ||
Pro/Ser | 45.6% (46) | 44.5% (122) | NS | 51.4% (37) | NS |
Ser/Ser | 17.8% (18) | 16.4% (45) | 13.9% (10) |
Abbreviations: Ala, alanine; GSTM1, glutathione S-transferase M1; GSTT1, glutathione S-transferase T1; NQO1, NAD(P)H:quinone oxidoreductase; NS, not significant; Pro, proline; Ser, serine; Val, valine.