Table 1.
Characteristics of the Study Population and the Unrelated Cord Blood Donors
| Pt No. | Diagnosis | Days of Life at Time of Transplant | HLA Match (No./Total No.) | HLA Mismatch | Blood Type Pt | Blood Type Donor | Pt Sex | Unit Sex |
|---|---|---|---|---|---|---|---|---|
| Cytopenias without other GVHD manifestations | ||||||||
| 2 | Thalassemia | 91 | 4/6 | A31/30;Bbl/7 | A+ | A+ | M | M |
| 6 | Krabbe | 29 | 4/6 | B57/8;DR0402/1302 | B+ | B+ | M | M |
| 12 | Krabbe | 117 | 5/6 | A11/29 | O+ | A+ | M | F |
| 13 | Krabbe | 26 | 4/6 | Abl/11;B39/18 | O+ | O+ | F | F |
| 15 | Krabbe | 22 | 5/6 | DR9/8 | O+ | O+ | F | F |
| 19 | Krabbe | 33 | 5/6 | A31/2 | A+ | A+ | M | F |
| Cytopenias with cGVHD | ||||||||
| 9 | MPS II | 44 | 5/6 | DR11/7 | O+ | A− | M | F |
| 10 | MPS I | 113 | 4/6 | A33/68;DR16/13 | B+ | A+ | M | M |
| 16 | MLD | 62 | 5/6 | A1/3 | O+ | O+ | M | F |
| 17 | Krabbe | 29 | 4/6 | B55/51;DR15/4 | A+ | O+ | F | M |
| No cytopenias or cGVHD | ||||||||
| 1 | MPS I | 88 | 5/6 | A28/29 | A+ | O+ | F | F |
| 3 | Krabbe | 55 | 4/6 | A30/25;B44/53 | O− | A+ | M | M |
| 4 | Krabbe | 29 | 4/6 | A2/33;B39/bl | AB+ | B+ | F | M |
| 5 | Tay-Sachs | 22 | 4/6 | B50/41;DRB1 1302/1303 | B+ | A+ | M | M |
| 7 | Krabbe | 37 | 5/6 | B40/58 | O+ | A− | F | M |
| 8 | MPS I | 62 | 5/6 | A68/2 | O+ | O+ | F | F |
| 11 | Krabbe | 26 | 5/6 | B18/44 | A− | A+ | M | M |
| 14 | Krabbe | 22 | 5/6 | B44/14 | A− | A+ | M | M |
| 18 | Krabbe | 18 | 4/6 | A25/11;B18/44 | B+ | A+ | F | M |
| Mean ± SD | 48 ± 31 | |||||||
| Median | 36 | |||||||
GVHD indicates graft-versus-host disease; cGVHD, chronic graft-versus-host disease; Pt, patient; bl, blank.