Table 1.
Molecular typing of treponemal DNA isolated from a set of 16 patients with two or more samples positive for treponemal DNA
| Patient no. | Syphilis stage | Sample | Material | Genotypes based on TP0136, TP0548, 23S rDNA | CDC subtype | Enhanced CDC subtype* |
|---|---|---|---|---|---|---|
| 1 |
Primary |
43K StI |
Swab |
SSS |
14d |
14d/f |
| |
|
44K StII |
Swab |
SSS |
14d |
14d/f |
| 2 |
Primary |
36K St |
Swab |
SU2R8 |
14d |
14d/g |
| |
|
37K |
Whole blood |
SU2R8 |
12d |
12d/g |
| 3 |
Primary |
93K |
Swab |
SXS |
14k |
14k/X |
| |
|
94K |
Whole blood |
XSX |
14e |
14e/f |
| 4 |
Primary |
891 |
Swab |
SSS |
14d |
14d/f |
| |
|
892 |
Swab |
SSS |
14p |
14p/f |
| 5 |
Primary |
91K |
Swab |
SSR8 |
14d |
14d/f |
| |
|
92K |
Whole blood |
SXX |
12e |
12e/X |
| 6 |
Primary |
C-150 |
Swab |
U1SS |
8b |
8b/f |
| |
|
D-151 |
Swab |
U1SS |
8d |
8d/f |
| 7 |
Primary |
8032 |
Swab |
SSR9 |
15d |
15d/f |
| |
|
8284 |
Swab |
SSR9 |
15d |
15d/f |
| 8 |
Primary |
19512 |
Swab |
SU2R8 |
14d |
14d/g |
| |
|
19527 |
Swab |
SU2R8 |
14b |
14b/g |
| 9 |
Primary |
15K St |
Swab |
SSS |
14d |
14d/f |
| |
|
16K |
Whole blood |
XSS |
XXe |
XXe/f |
| 10 |
Primary |
RL104BZ |
Swab |
SU2R8 |
14d |
14d/g |
| |
|
RL104AZ |
Whole blood |
XU2R8 |
14X |
14X/g |
| 11 |
Primary |
63K |
Swab |
SSR9 |
15d |
15d/f |
| |
|
62K |
Whole blood |
XSR9 |
15d |
15d/f |
| 12 |
Primary |
4K |
Swab |
SSS |
14d |
14d/f |
| |
|
5K |
Swab |
SSS |
14d |
14d/f |
| 13 |
Primary |
34K St |
Swab |
SSS |
14d |
14d/f |
| |
|
35K |
Whole blood |
XXS |
XXe |
XXe/X |
| 14 |
Primary |
RL116A |
Swab |
SU2R8 |
14e |
14e/g |
| |
|
RL116B |
Whole blood |
SXR8 |
14j |
14j/X |
| 15 |
Secondary |
15577 |
Swab |
SXS |
14d |
14d/X |
| |
|
15578 |
Swab |
SSS |
14d |
14d/f |
| 16 |
Secondary |
G-269 |
Swab |
SU1S |
14p |
14p/f |
| |
|
H-270 |
Swab |
SU1S |
14d |
14d/f |
| 17 |
Secondary |
51K |
Swab |
SSS |
14d |
14d/f |
| |
|
52K |
Swab |
SSS |
14d |
14d/f |
| 18 |
Secondary |
73K |
Swab |
SU2R8 |
14d |
14d/g |
| 74K | Whole blood | XXR8 | XXe | XXe/X |
X, the exact genotype was not determined.
*subtype identification based on CDC typing enhanced by sequence analysis of TP0548 between position 131–215 [14].